TILT Biotherapeutics advances cancer immunotherapy clinical trial achieving primary end point in the first cohort

Second dose escalation site approved in Nantes, France

Helsinki, Finland – 11 March 2021: TILT Biotherapeutics, a clinical-stage biotechnology company developing cancer immunotherapeutics, announces that it has achieved the primary endpoint of safety in its phase I trial with the first dose of its dual cytokine armed oncolytic adenovirus, TILT-123, at Herlev hospital in Denmark. No serious adverse events (SAEs) were observed in the trial for TILT-123 as a monotherapy or in combination with tumour infiltrating lymphocytes (TILs). The company has received regulatory approval to open a second clinical trial site at CHU Nantes, France, with 15 patients in total to be enrolled across the two sites. The clinical trial will now proceed to the second (of five) dose levels and expects interim data by the end of this year.

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